How Progesterone Plus Pregnenolone Advantages Your Hormones – Dr. Anna Cabeca

You’re in perimenopause or menopause and the recent flashes, temper swings, and mind fog are uncontrolled. Your instinct and your physician let you know it is because your estrogen is dropping. So after all it’s good to add estrogen to your life, proper? Earlier than you go there, I’d encourage you to discover how pregnenolone advantages your menopause expertise first.

In my personal observe, I’ve seen pregnenolone, particularly when mixed with progesterone, accomplish some fairly spectacular issues for menopausal ladies…all with out the tough and doubtlessly harmful unintended effects of estrogen remedy.

On this article, we’ll discover the advantages of pregnenolone, and the way it combines with progesterone to pack a hormone-balancing, menopause-busting punch. 

Your physique synthesizes pregnenolone from ldl cholesterol and from there — it will get changed into cortisol, progesterone, estrogen, testosterone, and dehydroepiandrosterone (DHEA).

Pregnenolone is primarily produced in your adrenal glands. However pregnenolone synthesis additionally takes place in different tissues, together with glial cells and neurons in your mind. (1)

Sometimes, as you age, your physique makes much less pregnenolone. Which is why pregnenolone supplementation throughout menopause is smart for lots of ladies. 

Pregnenolone dietary supplements have caught on not too long ago, for each women and men. Pregnenolone is especially well-liked as a result of not solely does it present the muse for creating different hormones, but it surely additionally has a popularity for serving to a wide range of psychological well being problems, together with melancholy. (2,3)

Pregnenolone for girls in menopause helps restore hormone stability by giving your physique extra of what it must make a bit of further of your intercourse hormones. However while you mix it with progesterone, it creates an much more complete method to managing hormone stability. This may be notably helpful for people experiencing a broad vary of menopausal disturbances — let’s check out a number of the methods this energy couple can help you. 

Pregnenolone is a precursor to many different hormones, together with progesterone. So supplementing with each pregnenolone and progesterone collectively might help get your hormones balanced extra simply.

Bear in mind, pregnenolone might be reworked by your physique into a variety of different hormones.

This implies irrespective of which hormones your physique is missing in the meanwhile, pregnenolone may assist stability issues out.

And we all know progesterone straight opposes that erratically-falling estrogen…so while you mix the 2 — collectively, they might assist handle a wider vary of challenges. Sometimes, I see this mixture easing scorching flashes and serving to your sleep and temper as properly. 

Pregnenolone is believed to have mood-stabilizing and memory-enhancing results. (4)

Plus, progesterone exerts a relaxing impact by interacting with GABA receptors within the mind. So, while you mix these two, they might extra successfully help cognition and temper regulation. Plus, they assist with these emotions of fear throughout menopause.

Progesterone has enjoyable, nearly sedative-like properties. Which you guess, may assist your sleep story change dramatically.

However, while you mix progesterone and pregnenolone, it’s the last word sleep help…as a result of pregnenolone has its personal calming results, too. Pregnenolone is the precursor for progesterone, and it’s additionally the precursor for different neurosteroids like allopregnanolone that help sleep patterns. (5,6)

Progesterone performs a job in bone formation and bone density. (7,8) Combining it with pregnenolone could supply further help for bone well being throughout menopause, a time when the chance of osteoporosis will increase — as a result of pregnenolone converts to progesterone and estrogen (one other key hormonal participant in bone density), and likewise as a result of it probably has bone-supportive properties of its personal, too. (9)

Each progesterone and pregnenolone play a job in pores and skin well being. Do you know progesterone helps to manage pores and skin elasticity? (10) That’s one of many causes I like to make use of it as a face cream in my Steadiness method nightly .

Pregnenolone might also help glowing pores and skin via its conversion into different hormones that profit the pores and skin, notably estrogen. (11) Collectively, these two hormones may assist preserve a younger pores and skin look throughout menopause.

Pregnenolone ranges fall as you age, there’s simply no getting round that. However there are particular issues you are able to do to assist encourage this significant hormone to stay round.

For one factor, your physique wants ldl cholesterol to make pregnenolone. Which means your food plan ought to embody wholesome sources of wholesome ldl cholesterol, like:

If you wish to enhance your pregnenolone ranges, it’s vital to encourage hormone stability with correct sleep hygiene, stress discount, and an total wholesome way of life that features loads of train. 

Pregnenolone is a precursor hormone. It’s on the high of the steroid hormone pyramid. That’s why we name it the mom hormone.

Pregnenolone will get transformed by your physique into progesterone, cortisol, androgens, and estrogens. (12) So, sure, pregnenolone might help help your estrogen ranges. We sometimes don’t see pregnenolone encourage estrogen dominance, although. It’s a a lot gentler and extra balanced method to growing estrogen than estrogen remedy.

Nevertheless, that additionally means in case you have or are liable to creating estrogen-dependent most cancers, it’s crucial you converse along with your oncologist earlier than beginning any kind of hormone remedy. 

Typically, pregnenolone dosage differs relying on the place you might be in your menopause journey and what your well being objectives are.

For ladies who take my Steadiness cream , which comprises each progesterone and pregnenolone, right here’s what I sometimes advocate:

For perimenopausal ladies:

Begin counting from the primary day you start bleeding; that is day 1. Then, on day 14 of your cycle, start making use of the Steadiness cream and proceed till day 28. Normally, you will apply one pump of the cream day by day from day 14 via day 28, which is the time from suspected ovulation till the start of your subsequent interval.

For postmenopausal or menopausal ladies:

Apply one pump of the cream for 25 days in a row, then take a 5-day break earlier than beginning the cycle once more. Alternatively, you would possibly use the cream 5 to six days per week, making certain to take 1 to 2 relaxation days throughout the week or comply with the particular directions offered by your healthcare skilled.

My Steadiness cream comprises about 20 mg of progesterone and 10 mg of pregnenolone in a single pump. 

I at all times advocate taking pregnenolone and progesterone at evening, to allow them to help you in drifting off to sleep.

When you take them too early within the day, you could possibly end up desirous to take a nap!

While you begin taking a pregnenolone complement, give it time.

So most of the ladies who use my Steadiness cream see outcomes after just a few functions.

However there are various who don’t discover the distinction till they’ve used it for 4-8 weeks, so keep it up.

It’s essential to be constant when making use of Steadiness . That’s one of many major troubles I see — ladies neglect to make use of their progesterone and pregnenolone frequently. Except you employ it recurrently, you gained’t see the advantages!

I’ve to level out right here that pregnenolone is a generally misspelled phrase! Listed below are a number of the variations I’ve seen, even in scientific literature:

• Pregenelone

• Pregnalone

• Pregenolone

• Pregnelone

• Pregnenalone

• Pregnanalone

• Pragnenalone

So if you happen to’re on the lookout for pregnenolone and having hassle discovering it, it could possibly be since you’re spelling it fallacious 😉 

Pregnenolone is such a captivating hormone. And it performs such an important function in your temper, reminiscence, sleep, bones, sleep, pores and skin, and total hormone stability throughout menopause.

When mixed with bioidentical progesterone, it’s an unstoppable drive for menopausal ladies all over the place.

Be sure you take a look at my Steadiness cream , which comprises bioidentical variations of each of those highly effective hormones to start out feeling like your outdated self once more!