Image of podcast artwork. Please email for a link to listen to our professional podcast about caries.

Prescription excessive fluoride toothpaste may help sufferers successfully stop and management caries whereas exterior of the observe setting. 1 It is a easy, evidenced-based means for serving to sufferers keep away from extra caries onset or development.  

Prescription excessive fluoride toothpaste may help stop caries by inhibiting demineralisation and selling remineralisation. 2

Excessive fluoride toothpastes are available two strengths – a 2800ppm sodium fluoride paste can be utilized by these over the age of 10, and a better power 5000ppm sodium fluoride which can be prescribed for these aged 16 years and over. 3, 4, 5, 6

Prescription excessive fluoride toothpaste must be prescribed for sufferers with elevated threat (moderate-high chance) of creating dental caries. 1 This helps sufferers to manage their preliminary caries lesions. 7, 8

One tube of excessive fluoride toothpaste lasts a affected person roughly one month, and dentists could prescribe as much as six months at a time, in-line with their subsequent recall appointment. These prescriptions might be time post-dated in order that sufferers choose their prescription up in batches reasonably than multi function go.

Extra details about the traits of excessive fluoride toothpaste might be discovered on the MHRA web site.

Figuring out moderate-high threat caries sufferers

There are lots of threat assessments obtainable to find out a affected person’s chance and severity of caries.

This is only one instance of caries threat evaluation: 9


Social historical past

Medical historical past

Dietary historical past

Use of fluoride

Plaque management


Medical proof

Excessive caries threat

Socially disadvantaged.

Excessive presence of caries in siblings.

Low data of dental illness.

Irregular attender.

Prepared availability of snacks.

Low dental aspirations.

Medically compromised.

Bodily disabilities.


Lengthy-term medicines.

Cariogenic drugs.

Frequent sugar consumption.

Ingesting un-fluoridated water.

No fluoride dietary supplements.

Non-fluoride toothpaste.

Rare, ineffective cleansing.

Poor handbook cleansing.

Low circulate fee.

Low buffering capability

Excessive S mutans and lactobacillus counts.

New lesions, untimely extractions, anterior caries or restorations, a number of restorations.

No fissure sealants.

Fastened equipment.


Partial dentures.

Average caries threat People who don’t clearly match into excessive or low caries threat classes are thought of to be at average caries threat.

Low caries threat

Socially advantaged.

Low caries in siblings.

Dentally conscious.

Common attender.

Work doesn’t enable common snacks.

Excessive dental aspirations.

No medical issues.

No bodily issues.

Regular saliva circulate.

No long-term treatment.

Rare sugar consumption.

Ingesting fluoridated water.

Fluoride dietary supplements used.

Fluoride toothpaste used.

Frequent, efficient cleansing.

Good handbook cleansing.

Regular circulate fee.

Excessive buffering capability

Low S mutans and lactobacillus counts.

No new lesions.

Nil extractions for caries.

Sound anterior tooth.

No or few restorations.

Restorations inserted years in the past.


No equipment.

Sufferers at elevated caries threat sufferers aged ten years and over, these with caries current, orthodontic home equipment, a extremely cariogenic weight loss program or treatment inflicting dry mouth, could possibly be prescribed a 2880ppm fluoride toothpaste. 1

Sufferers aged 16 years and over with elevated caries threat, current or potential for root caries, dry mouth, orthodontic home equipment, overdentures, these with extremely cariogenic weight loss program or treatment inflicting dry mouth, could possibly be prescribed a fluoride 5000ppm toothpaste. 1


  1. Public Well being England (2017) ‘Delivering higher oral well being: an evidence-based toolkit for prevention’, Third Version, UK.
  2. Baysan A, Lynch E, Ellwood R, Davies R, Petersson L, Borsboom P. Reversal of main root caries utilizing dentifrices containing 5,000 and 1,100 ppm fluoride. Caries Res. 2001 Jan-Feb;35(1):41-6. doi: 10.1159/000047429. PMID: 11125195.
  3. Colgate (2020) ‘Colgate® Duraphat® 5000ppm Fluoride’, on-line at, accessed October 2020.
  4. Colgate-Palmolive (U.Okay.) Ltd (2020) ‘Abstract of Product Traits,’ Duraphat 2800ppm fluoride toothpaste. On-line at https://mhraproducts4853.blob.core.home windows.web/docs/c0e452136f37b21ae14dae330bc55c62b0e931fb
  5. Colgate-Palmolive (U.Okay.) Ltd (2020) ‘Abstract of Product Traits’, Duraphat 5000ppm fluoride toothpaste. On-line at https://mhraproducts4853.blob.core.home windows.web/docs/993ca2d10345c940c4649fd8c98042f68fe00d51
  6. Colgate-Palmolive (U.Okay.) Ltd (2014) ‘Duraphat® 5000ppm Fluoride Toothpaste’, Bundle Leaflet: Data for the consumer, on-line at https://mhraproducts4853.blob.core.home windows.web/docs/f7686217b083fc71959d19152bb6eab6ea5dad82.
  7. Schirrmeister JF, Gebrande JP, Altenburger MJ, Mönting JS, Hellwig E. Impact of dentifrice containing 5000 ppm fluoride on non-cavitated fissure carious lesions in vivo after 2 weeks. Am J Dent. 2007 Aug;20(4):212-6. PMID: 17907481.
  8. Biesbrock AR, Gerlach RW, Bollmer BW, Faller RV, Jacobs SA, Bartizek RD. Relative anti-caries efficacy of 1100, 1700, 2200, and 2800 ppm fluoride ion in a sodium fluoride dentifrice over 1 yr. Neighborhood Dent Oral Epidemiol. 2001 Oct;29(5):382-9. doi: 10.1034/j.1600-0528.2001.290508.x. PMID: 11553111.
  9. FGDPUK (2016) ‘Medical Examination and Document-Retaining: Good Follow Tips’, printed by College of Common Dental Follow (UK), The Royal School of Surgeons of England. United Kingdom.